Total number of Results for c.281G>C (p.Gly94Ala) are 6
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)
Efficacy
for wild (%)
Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0932 CUGCUGACAAAGAUGCUGU
GACGACUGUUUCUACGACA
85 90 -5 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.281G>C (p.Gly94Ala) rs12191243
14981234
aspsirna0933 CAAAGAUGCUGUGGCCGAU
GUUUCUACGACACCGGCUA
78 65 13 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.281G>C (p.Gly94Ala) rs12191243
14981234
aspsirna0934 CAAAGAUGCUGUGGCCGAU
GUUUCUACGACACCGGCUA
80 34 46 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.281G>C (p.Gly94Ala) rs12191243
14981234
aspsirna0936 GACAAAGAUGCUGUGGCCGAU
CUGUUUCUACGACACCGGCUA
87 20 67 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.281G>C (p.Gly94Ala) rs12191243
12930974
aspsirna3567 GACAAAGAUGCUGUGGCCGAU
CUGUUUCUACGACACCGGCUA
87 20 67 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.281G>C (p.Gly94Ala) rs12191243
EP1567539B1
aspsirna3568 GACAAAGAUGCUGUGGCCGAU
CUGUUUCUACGACACCGGCUA
87 20 67 SOD1 Amyotrophic Lateral Sclerosis (ALS) c.281G>C (p.Gly94Ala) rs12191243
EP1567539B1